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Choose collection locationSTI & STD · Individual laboratory test
Treponema Pallidum Hemagglutination Assay (TPHA)
TPHA detects antibodies directed against the organism that causes syphilis. These antibodies often remain after an infection has been treated.
Price for this test on its ownAED 205Test price AED 105
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
- Sample
- Serum
- Laboratory turnaround
- 24 hours
- Collection
- Dubai
- Laboratory
- Intel Lab
Understanding the test
What does the TPHA test measure?
Also called Syphilis Confirmation (TPHA)
TPHA can help clarify a reactive screening result or evidence of prior syphilis. Share any earlier test results and treatment records with the clinician.
When it may be requested
Confirming treponemal antibodies
TPHA can help clarify a syphilis screening result as part of a testing algorithm.
Checking previous infection history
Past treatment and earlier titres help a clinician interpret a positive result.
Before your sample
Prepare for collection
SpecimenSerum
Your checklist
No fasting is generally needed. Bring prior syphilis results and dates of treatment or possible exposure; antibodies may persist after treatment.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
Understanding your result
24 hoursLaboratory turnaround
Result guideTreponema Pallidum Hemagglutination Assay (TPHA)
Reading your result
A reactive treponemal antibody alone cannot distinguish an untreated new infection from a treated old infection. Clinical history and other serology supply that distinction.
What can affect it
- Treponemal antibodies often remain positive after treatment and cannot alone establish active infection.
From sample to follow-up
Your testing journey
Laboratory testTreponema Pallidum Hemagglutination Assay (TPHA)
- Specimen
- Serum
- Turnaround
- 24 hours
Open your laboratory report
Look for Treponema Pallidum Hemagglutination Assay (TPHA) in your report. Use the sample type and collection time when comparing it with an earlier report.
Explore Smart Report
Discuss the next step
Pair TPHA with the RPR result and previous treatment dates when discussing whether a finding represents current or past infection.
Clinical expertise
Your laboratory team
Patient questions
Before you book
Can this tell me whether previous treatment worked?
TPHA can remain reactive despite successful treatment. Clinicians use clinical history and appropriate non-treponemal titres to assess treatment response.
What is the difference between TPHA and RPR?
TPHA looks for antibodies specific to syphilis that often remain detectable after treatment. RPR and VDRL titres are used for follow-up because they often fall, although some people stay reactive. Bring earlier results and treatment dates so your clinician can compare the same type of test over time.
What does a non-reactive TPHA result mean?
No treponemal antibodies were detected. Testing early can miss an infection. If you had sexual contact with a partner in the 90 days before they were diagnosed with early syphilis, seek care promptly. Treatment is recommended even if your blood test is negative. For other possible exposures, your clinician can advise when to repeat testing.
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Your next step
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Sources & further reading
Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.