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Choose collection locationSTI & STD · Individual laboratory test
RPR (Rapid Plasma Reagin)
RPR is a non-treponemal blood test used in syphilis assessment. Where titres are reported, a clinician may use changes over time to follow treatment.
Price for this test on its ownAED 155Test price AED 55
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
- Sample
- Serum
- Laboratory turnaround
- 24 hours
- Collection
- Dubai
- Laboratory
- Intel Lab
Understanding the test
What does RPR (Rapid Plasma Reagin) measure?
Also called Syphilis Screen (RPR)
RPR may be requested after a possible exposure or to monitor someone with a known syphilis diagnosis. Previous titres and treatment dates are particularly useful.
When it may be requested
Screening in a syphilis evaluation
RPR is a non-treponemal test that usually needs a treponemal test for diagnostic interpretation.
Following treatment response
A clinician may compare titres over time using the same method where possible.
Before your sample
Prepare for collection
SpecimenSerum
Your checklist
No fast is needed. Tell the clinician about previous syphilis treatment, pregnancy and any earlier RPR titres to support accurate comparison.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
Understanding your result
24 hoursLaboratory turnaround
Result guideRPR (Rapid Plasma Reagin)
Reading your result
A reactive RPR needs a companion treponemal test when establishing a diagnosis. Trends used for follow-up should be interpreted using the appropriate method and clinical history.
What can affect it
- RPR can react for reasons other than syphilis and can be negative early in infection.
From sample to follow-up
Your testing journey
Laboratory testRPR (Rapid Plasma Reagin)
- Specimen
- Serum
- Turnaround
- 24 hours
Open your laboratory report
Look for RPR (Rapid Plasma Reagin) in your report. Use the sample type and collection time when comparing it with an earlier report.
Explore Smart Report
Discuss the next step
Bring past titres with their dates and prior treatment records so the clinician can distinguish a new finding from a change after treatment.
Health packages
Packages that include this test
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Clinical expertise
Your laboratory team
Patient questions
Before you book
Why might I need a second kind of test?
RPR can react for reasons other than syphilis. A treponemal test, examination and treatment history help interpret a reactive result.
What is the difference between RPR and TPHA?
RPR measures antibodies that can appear with syphilis and with some other conditions. Its titre often falls after treatment but can remain detectable. TPHA measures antibodies more specific to syphilis and often stays positive after successful treatment. Clinicians interpret both results alongside symptoms and past treatment.
Why is RPR tested in pregnancy?
Syphilis screening is a routine part of prenatal care, because untreated infection can pass to the baby and treatment during pregnancy protects both. Pregnancy itself is also a recognised cause of a biological false positive, so tell the team if you are pregnant, and a reactive result is always confirmed with a treponemal test before anything is concluded.
My RPR went from 1:32 to 1:8. What does that change mean?
That is a fourfold fall, a change clinicians use when assessing response to treatment. Compare RPR with another RPR, ideally from the same laboratory. RPR and VDRL numbers cannot be compared directly. Your clinician also considers the time since treatment, symptoms and any new exposures.
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Sources & further reading
Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.