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Choose collection locationEndocrinology · Individual laboratory test
This profile pairs the pituitary signal, TSH, with total T4 and total T3. The totals include hormone that is carried on proteins in the blood.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Total T3, T4 & TSH
A clinician may select the total profile when earlier results or the referral specify total T3 and total T4. These values include hormone carried on proteins.
Total thyroid hormone measurements include both the amount bound to proteins and the free fraction.
The clinician reads the total hormones in relation to TSH and the reason for testing.
Inside this test
Before your sample
No fast is generally required. Agree thyroid medicine timing in advance, mention biotin or oestrogen treatment and tell the clinician if you are pregnant.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
24 hoursLaboratory turnaround
Changes in binding proteins sometimes move both totals without a corresponding change in thyroid activity. Results are easiest to compare when the same type of profile is used.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Thyroid Profile, Total in your report. Use the sample type and collection time when comparing it with an earlier report.
Explore Smart Report
Mention pregnancy or hormone treatment and clarify whether earlier results were total or free hormone measurements.
Patient questions
Pregnancy and some medicines can change carrier proteins and therefore the total measurements. Tell the clinician about these circumstances when comparing results.
Pregnancy raises the carrier protein that thyroid hormone travels on, so more hormone is held in the blood even though the amount available to your tissues is unchanged. Your doctor will read the TSH and, if needed, free hormone levels to check function.
Total counts every hormone molecule in the blood, most of which is attached to carrier proteins and cannot act. Free counts only the unbound portion that can enter cells. The free measurement is closer to what your body actually experiences.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.