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Choose collection locationEndocrinology · Individual laboratory test
Total T3 includes both bound and free triiodothyronine. Its interpretation depends partly on the proteins that carry thyroid hormones.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Total Thyroid Hormone (T3)
Clinicians may select total T3 when investigating patterns of increased thyroid activity. It includes both hormone bound to proteins and hormone circulating freely.
Total T3 can help investigate excess thyroid activity when the clinical picture calls for it.
A clinician may compare T3 with T4, TSH and previous results.
Before your sample
Eat normally unless another test requires fasting. Tell the team about biotin, thyroid medicines, pregnancy or oestrogen treatment before a total T3 measurement.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
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24 hoursLaboratory turnaround
Changes in carrier proteins and illness can affect total T3. Use the interval for total T3 rather than interpreting it as a free T3 result.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Tri-Iodothyronine, Total (T3) in your report. Use the sample type and collection time when comparing it with an earlier report.
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Confirm that the earlier measurement was also total T3 and discuss the result together with TSH and T4.
Patient questions
Changes in carrier proteins can alter the total while the unbound fraction changes less. TSH, medicines and pregnancy status can help interpret the difference.
A total T3 test on its own usually needs no fast. Tell the team which thyroid medicines or supplements you take. Follow your prescriber’s timing instructions for your dose, especially if you take a medicine containing T3.
Yes. Severe calorie restriction, prolonged fasting and significant malnutrition reduce the conversion of T4 into T3, and the fall is a normal adaptation rather than thyroid disease. Eat normally in the days before the test so the result reflects your usual state, and tell your doctor if you have been on a very restrictive diet.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.