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Choose collection locationEndocrinology · Individual laboratory test
This profile combines TSH with free T4 and free T3. The free values describe the portions circulating independently of carrier proteins.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Free T3, T4 & TSH
A free thyroid profile may be requested when symptoms and TSH do not tell the whole story. It measures the pituitary signal and two circulating hormone fractions.
TSH and the free thyroid hormone concentrations show different parts of the same feedback system.
The pattern helps a clinician decide whether a repeat specimen or a different investigation is useful.
Inside this test
Before your sample
No fast is usually needed. Confirm timing relative to your thyroid tablet and tell the team about biotin, which can affect some assay methods. Use similar timing for repeat monitoring.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
24 hoursLaboratory turnaround
Patterns across TSH, free T4 and free T3 are assessed together. Acute illness and some medicines or supplements can affect the measurements.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Thyroid Profile, Free in your report. Use the sample type and collection time when comparing it with an earlier report.
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Tell the clinician the time of your last thyroid tablet and any biotin use when comparing the three values with previous results.
Patient questions
TSH is the signal from the pituitary. Free T4 and free T3 reflect circulating thyroid hormones. Their pattern helps your clinician investigate a result that looks unexpected on its own.
A suppressed TSH with high free hormones suggests an overactive thyroid. The commonest cause is Graves' disease; others are a toxic nodule or multinodular goitre, thyroiditis where stored hormone leaks from an inflamed gland, too high a dose of thyroid medication, or excess iodine from contrast dye or supplements. Your doctor uses antibodies or a scan to tell these apart.
Yes. High-dose biotin, often found in hair, skin and nail supplements, interferes with several thyroid assays and can produce a convincingly abnormal set of results in someone whose thyroid is normal. If you take biotin, mention it; your doctor may advise pausing it for a short period before the sample.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.