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Choose collection locationImmunology / Serology · Individual laboratory test
Rheumatoid factor is an antibody that can support an assessment of inflammatory joint disease. It may also occur with other conditions or in healthy people.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Rheumatoid Arthritis Marker
A clinician may order rheumatoid factor when persistent joint swelling, stiffness and examination findings suggest inflammatory arthritis.
Rheumatoid factor may support assessment when joint symptoms suggest an inflammatory disease.
The clinician may consider anti-CCP, inflammatory markers and examination findings.
Before your sample
This measurement requires no fast. Tell the clinician about steroid, biologic or other immune-modifying treatment and the duration of your joint symptoms.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
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24 hoursLaboratory turnaround
A positive value also occurs in other conditions and sometimes in healthy people. A negative value does not end an investigation when the clinical findings remain persuasive.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Rheumatoid Factor (RA), Quantitative in your report. Use the sample type and collection time when comparing it with an earlier report.
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Make a note of which joints are swollen, how long stiffness lasts and any accompanying tests for your rheumatology review.
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Patient questions
No. Some people with rheumatoid arthritis have no detectable rheumatoid factor. The joint examination, history and other tests remain important.
Yes. Some infections, including hepatitis C, can be associated with a positive rheumatoid factor. Tell your clinician about recent illness, ongoing infections and any joint swelling or morning stiffness. A positive result alone cannot establish rheumatoid arthritis.
No. The antibody is found in several other conditions and in a proportion of healthy older adults with no joint disease. Your doctor reads it together with your symptoms, examination, imaging and other blood tests before reaching any conclusion.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.