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Biochemistry · Individual laboratory test

Protein, Total, Serum

Total serum protein adds together albumin and globulins. Changes in fluid balance or in one group of proteins can affect the total.

Price for this test on its ownAED 125Test price AED 25
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Dr Nirupama SabhapathyClinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Folded protein ribbons form a still life inside a transparent prism.
Sample
Serum
Laboratory turnaround
24 hours
Collection
Dubai
Laboratory
Intel Lab
Protein, Total, Serum specimen guide showing serum.

Understanding the test

What does the Total Serum Protein test measure?

Also called Total Blood Protein

A clinician may use total serum protein to investigate swelling or an unexpected protein measurement. It is also part of some liver and metabolic assessments.

When it may be requested

Unexplained swelling

A clinician may consider protein concentration together with albumin and urine findings.

Changes in globulins

A raised total may prompt more specific blood protein measurements.

Before your sample

Prepare for collection

SpecimenSerum
Your checklist0 of 2 ready

No fasting is usually needed. Maintain your normal fluid intake within medical advice; dehydration or unusually large fluid intake can change the concentration of blood proteins.

A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.

Smart Report

Understanding your result

24 hoursLaboratory turnaround

Intel LabResult guide

Protein, Total, Serum

Reading your result

The albumin and globulin fractions can move in opposite directions. Fluid balance matters because this is the concentration of protein in a blood sample.

What can affect it

  • Albumin and globulins can offset one another, leaving an apparently normal total.

From sample to follow-up

Your testing journey

Intel Lab specimen collection kit

Arrange your collection

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.

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Intel Lab
Laboratory testProtein, Total, Serum
Specimen
Serum
Turnaround
24 hours

Open your laboratory report

Look for Protein, Total, Serum in your report. Use the sample type and collection time when comparing it with an earlier report.

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clinician and adult patient discussing laboratory results

Discuss the next step

Ask which protein fraction accounts for the total and whether a more specific protein measurement would clarify it.

Clinical expertise

Your laboratory team

Patient questions

Before you book

Why look at albumin and globulin separately?

An increase in one fraction can offset a fall in another. The split may reveal a change that the total alone would conceal.

What does a high total protein mean?

A high total protein most often reflects dehydration, which concentrates every protein, or a rise in globulins. Raised globulins can come from chronic infection, long-standing inflammation, autoimmune disease or, less often, a plasma-cell disorder such as myeloma. Your doctor checks albumin, globulin and their ratio to tell these apart.

My total protein is normal, so why is my doctor still investigating?

Because the total is a sum of two things that can move in opposite directions. A low albumin paired with a raised globulin can produce a perfectly ordinary total while representing a real change in the balance, which is exactly what the albumin-to-globulin ratio is there to reveal.

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Total Serum Protein test at home.

Sources & further reading

Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .

Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.