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Choose collection locationUrine Studies · Individual laboratory test
Creatinine clearance combines a timed urine collection with a blood creatinine measurement to estimate kidney filtration.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Kidney Clearance Test
This test may be selected when a clinician needs a timed estimate of kidney clearance in addition to a serum-based estimate.
The urine and blood results can provide another estimate when serum creatinine alone leaves uncertainty.
A clinician may compare the result with earlier renal findings, particularly when a correctly timed collection is available.
Before your sample
Obtain the supplied 24-hour container and its storage instructions. Discard the first urine and note the time, then collect every void through the same time the next day. Arrange the accompanying blood draw as instructed and report any missed portion.
This order pairs a blood sample with a full 24-hour urine collection. Follow the laboratory’s start and finish instructions and arrange the blood draw within the collection plan.
Smart Report
24 hoursLaboratory turnaround
A missed urine sample or a mistimed blood draw can distort the calculation. Keep an accurate record of the day of collection.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Creatinine Clearance Test in your report. Use the sample type and collection time when comparing it with an earlier report.
Explore Smart Report
Take the collection times, total urine record and paired blood result to the review. Mention any missed specimen.
Patient questions
The calculation compares what leaves in urine over a recorded time with the level in the blood. A missed urine portion or incorrect timing can distort the estimate.
A low creatinine clearance points towards reduced kidney filtration, from chronic kidney disease, acute injury caused by dehydration or severe infection, obstruction to urine flow, heart failure or some medicines. Before reaching that conclusion, your doctor checks that the collection was complete, because a missed passing of urine falsely lowers the result and is the commonest reason it misleads.
A higher than expected creatinine clearance is often not a problem. Filtration normally increases in pregnancy, and a high protein intake or greater than average muscle mass can lift the figure. It can also appear in the early phase of diabetes, when the filtering units work harder than usual, or if urine was collected beyond the timed window.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.