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Endocrinology · Individual laboratory test

Cortisol (AM/PM)

Cortisol normally follows a daily rhythm. This test compares a morning sample with a second sample at the time specified by your clinician.

Price for this test on its ownAED 155Test price AED 55
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Dr Nirupama SabhapathyClinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Two tubes frame a transition from morning sunlight to evening shade.
Sample
Serum
Laboratory turnaround
24 hours
Collection
Dubai
Laboratory
Intel Lab
Cortisol (AM/PM) specimen guide showing serum.

Understanding the test

What does the Cortisol (AM/PM) test measure?

Also called Stress Hormone (AM / PM)

A paired measurement can show whether the expected morning-to-later change is present. Work pattern, sleep and the timing of medicines may be especially relevant.

When it may be requested

Following a daily rhythm

Cortisol normally varies throughout the day, so the two labelled times are part of the result.

Discussing adrenal function

A clinician may use the paired readings to decide whether more specific hormone testing is warranted.

Inside this test

What the laboratory looks for

In this test
  • Morning cortisol
  • Later cortisol at the time specified by your clinician

Before your sample

Prepare for collection

SpecimenSerum
Your checklist0 of 2 ready

Follow your clinician's sampling times and tell the team about your waking time, shift work and steroid medicines, including inhaled or topical products. Do not change prescribed steroids without medical guidance.

The morning and later blood samples must follow the schedule on your referral. At home the team returns for the second sample. In Deira, confirm both collection times with the team.

Smart Report

Understanding your result

24 hoursLaboratory turnaround

Intel LabResult guide

Cortisol (AM/PM)

Reading your result

Results are compared with intervals appropriate to their sampling times. One pair cannot confirm an adrenal or pituitary diagnosis without the clinical context and, sometimes, further testing.

What can affect it

  • A changed sleep schedule, acute illness and steroid medicines can complicate interpretation.

From sample to follow-up

Your testing journey

Intel Lab specimen collection kit

Arrange your collection

Choose where to be tested and plan around the required sampling times. The care team will coordinate your collection schedule.

Choose collection location
Intel Lab
Laboratory testCortisol (AM/PM)
Specimen
Serum
Turnaround
24 hours

Open your laboratory report

Look for Cortisol (AM/PM) in your report. Use the sample type and collection time when comparing it with an earlier report.

Explore Smart Report
clinician and adult patient discussing laboratory results

Discuss the next step

Keep the actual times of both samples, waking time and any steroid use together with the report for your clinician.

Health packages

Packages that include this test

Compare the other tests in each package before choosing.

Clinical expertise

Your laboratory team

Patient questions

Before you book

Must I spend the whole day at the laboratory?

The useful information comes from two timed samples. Confirm the morning and later appointment times before visiting Deira. Tell the team about shift work, disrupted sleep or steroid medicines.

What does a low morning cortisol mean?

A low morning cortisol raises the question of an underactive adrenal gland, as in Addison's disease, or a pituitary problem reducing the signal to the adrenals. It is also common after prolonged steroid treatment, when the adrenals have become inactive and need time to recover. Your doctor usually confirms it with a stimulation test before drawing conclusions.

Does a high cortisol mean Cushing's syndrome?

A high blood cortisol can occur during illness or stress. Morning and afternoon results alone cannot diagnose Cushing’s syndrome. When symptoms suggest it, an endocrinologist may choose a late-night saliva test, a 24-hour urine cortisol collection or a dexamethasone suppression test.

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Cortisol (AM/PM) test at home.

Sources & further reading

Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .

Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.