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Choose collection locationUrine Studies · Individual laboratory test
This spot urine ratio compares total protein with creatinine to estimate protein loss while accounting for concentration.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Urine Protein/Creatinine Ratio
A clinician may use this ratio to estimate the extent of urinary protein loss without a full-day collection. It can be useful when following an existing kidney concern.
This ratio compares total protein and creatinine in the same urine specimen.
A clinician can follow changes without relying solely on a protein concentration from a dilute or concentrated sample.
Before your sample
A first-morning clean-catch sample is preferred where possible. Avoid collecting immediately after strenuous exercise unless your clinician has asked for that timing.
Use the collection container and instructions supplied for this order. The sampling method depends on the test, so confirm the instructions before collecting at home.
Smart Report
24 hoursLaboratory turnaround
The ratio partly corrects for dilution. Muscle mass and the clinical setting influence how closely it represents actual daily protein loss.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Protein / Creatinine Ratio, Random Urine in your report. Use the sample type and collection time when comparing it with an earlier report.
Explore Smart Report
Compare like-for-like ratios and record whether the specimen was first-morning and whether illness or exercise could have affected it.
Patient questions
No. This test looks at total protein. An albumin-to-creatinine ratio focuses on albumin, so the tests may be used for different clinical questions.
This ratio estimates protein loss from one specimen, so you do not have to collect every void over a day. Protein excretion can vary during the day. For some kidney conditions your clinician may still request a timed collection to measure the amount passed over that period.
It can indicate progression, but one value is never enough. Your doctor looks at several results over time together with blood tests and blood pressure before drawing any conclusion.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.