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Choose collection locationDiabetes · Individual laboratory test
C-peptide is released alongside insulin made by your pancreas. A fasting sample can help a clinician understand how much insulin your own body is producing.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Insulin Production Marker
Clinicians may assess C-peptide when the amount of insulin produced by the pancreas is uncertain. It can also contribute to a specialist investigation of low glucose.
C-peptide can help distinguish the pancreas's production from injected insulin.
Measured with glucose, it may contribute to investigation of unexplained low readings.
Before your sample
Follow the fasting instructions for the booked collection. If you use insulin or other glucose-lowering medicine, agree timing with the prescribing clinician before fasting.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
24 hoursLaboratory turnaround
Injected insulin contains no C-peptide. Kidney function and the glucose at collection still affect what a measured C-peptide means.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for C-Peptide, Fasting in your report. Use the sample type and collection time when comparing it with an earlier report.
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Ask whether the blood glucose recorded at the same time supports the interpretation of your C-peptide result.
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Patient questions
The expected insulin response depends on whether glucose is low or high. A C-peptide value has different implications in those two settings.
Two reasons. Insulin is partly removed by the liver as soon as it is released, so blood insulin fluctuates more; and if you take insulin by injection or pump, an insulin measurement cannot distinguish that from your own. C-peptide is produced only by your pancreas, so it reflects your own output.
The kidneys are the main route by which this fragment leaves the blood. When kidney function is reduced it accumulates, so the level can look high even when the pancreas is producing normally. Your doctor allows for this when interpreting the result.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.