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Choose collection locationHormones & Fertility · Individual laboratory test
Estradiol is one of the main oestrogens. Its level varies across the menstrual cycle and can be used in fertility or other hormone assessments.
Clinical authorDr Nirupama SabhapathySpecialist Clinical Pathology
Understanding the test
Also called Estrogen (E2)
The timing of estradiol measurement depends on whether the question concerns cycle function, ovarian stimulation or a different hormone assessment.
Estradiol changes as follicles develop and may be measured at a specified cycle phase.
Serial measurements can help a specialist interpret the response to fertility treatment.
Before your sample
Follow the cycle day or fertility-treatment schedule on your referral. Record your last period, relevant hormone medicines and the time of the most recent dose as directed.
A clinician takes a small sample of blood from a vein. The laboratory uses serum, the liquid separated from the blood after it clots.
Smart Report
24 hoursLaboratory turnaround
The same value can mean different things at different points of a cycle. Record cycle dates, pregnancy status or relevant hormone treatment when applicable.
From sample to follow-up

Choose your location, add the test to your care bag and select a time. If you are booking for someone else, assign the test to them in checkout.
Choose collection locationLook for Estradiol (E2) in your report. Use the sample type and collection time when comparing it with an earlier report.
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Write down the cycle day or the stage of fertility treatment on the report before comparing it with another measurement.
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Patient questions
The expected value changes as a follicle develops and ovulation approaches. Record the cycle day and any fertility medication for meaningful interpretation.
During ovarian stimulation several follicles grow at once, and each one produces oestrogen, so estradiol rises as they develop. Repeated measurements help the fertility team follow how the ovaries are responding to the medication and decide on timing and dose. High readings in this setting are expected rather than a sign of disease.
It can be part of the explanation, but low estradiol is a finding rather than a cause. Your doctor will look at FSH, LH and prolactin at the same time to work out whether the pituitary signal, the ovarian response, or something else such as weight, illness or stress lies behind it.
Yes. A baseline estradiol for ovarian reserve is usually drawn with FSH on cycle days 2 to 4. During IVF stimulation, the fertility team sets the appointment day according to the treatment plan.
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Written by Dr Nirupama Sabhapathy, Specialist Clinical Pathology. Medically reviewed by Dr Joyce Jose, Specialist Clinical Pathology, on .
Catalogue information and AED price checked on 2 November 2026. Clinical suitability, preparation, collection arrangements and turnaround are confirmed for your selected test.